Background and Aim: Sugar and Lipid disorders are the main risk factors for vascular abnormalities. Due to the gender and age, other variables can influence serum Fasting blood sugar and lipid levels, certifying the determination of population-specific reference interval. This study was designed to investigate the age-and gender-specific reference values for serum Fasting blood sugar (FBS), triglycerides (TG), TOTAL CHOLESTEROL (TC), low-density lipoprotein (LDL), high-density lipoprotein-CHOLESTEROL (HDL) in healthy Babolian adults. Methods: FBS, TC, TG, and HDL were calculating applying the colorimetric method. The Friedewald equation (LDL=TC− HDL− TG/5) was used to calculate LDL concentrations in individuals. After using the exclusion parameters, 519 participants (199 men and 320 women) aged ≥ 23 years were included. The Clinical Chemistry guidelines of the International Federation applied for characterizing the reference values for samples. Results: Reference values for serum FBS, TG, TC, LDL, HDL were 77. 01-107. 69 mg/dL, 35. 34-204. 38 mg/dL, 117. 97-242. 81 mg/dL, 47. 6-137. 16 mg/dL and 33. 29-67. 13 mg/dL in men. In women, reference values for serum FBS, TG, TC, LDL, HDL were 75. 03-107. 99, 27. 49-192. 33 mg/dL, 125. 84-244. 32 mg/dL, 44. 08-139. 48 mg/dL and 36. 66-81. 1 mg/dL. FBS, TG, and LDL parameters were higher in men, and TC and HDL parameters were higher in women. Conclusion: Reference values for serum FBS, TC, TG, LDL, HDL in healthy Babolian adults were specified, and these data could supply a clear pathway for better decision making in both clinical settings and prevention.

Background and Objectives: In recent years, prevalence of hyperCHOLESTEROLemia has increased, especially in elderly people who are susceptible to increased levels of TOTAL CHOLESTEROL. Apples include active ingredients that act as antioxidant, anti-proliferation, lipid oxidation inhibitor, anti-hyperCHOLESTEROL, and weight loss agents. The aim of this study was to investigate how Fuji apple juice affected TOTAL CHOLESTEROL levels in elderly people. Materials and Methods: This study was an experimental study that was carried out on 26 elderly people with a history of hyperCHOLESTEROLemia, dividing into two major groups using randomized pre post test control group design with randomized controlled trial. The control group (G0) received no medication, while the experimental group (G1) received the Fuji apple juice of 200 ml for 14 days. Paired t-test and independent t-test were used to analyze the results. Results: The mean pre-post G0 TOTAL CHOLESTEROL increased by 22. 38 with, no significant changes (p > 0. 05). The mean pre-post G1 TOTAL CHOLESTEROL decreased by 27. 62, suggesting statistically significant changes (p < 0. 05). Conclusions: In conclusion, use of 200 ml of Fuji apple juice for 14 days decreased TOTAL CHOLESTEROL levels in hyperCHOLESTEROLemia elderly people.